… Structure determination of peptide-RNA complexes produce atomic resolution … to target it
with our BIV-TAR mimetics even if this interaction is distinct from the TAR-Tat interactions in that …

… Structure determination of peptide-RNA complexes produce atomic resolution … to target it
with our BIV-TAR mimetics even if this interaction is distinct from the TAR-Tat interactions in that …

… of cyclic peptides that target more complex tertiary folds of … Structural studies of this new
RRM in complex with the TAR … structure of the peptide:RNA complex further revealed that the …

… human disease, making them an unexploited target for … recognition elements for BIV-TAR
binding by sandwiching … (B) Structure of pre-miR21-L50 complex with nucleotides that make …

… -Tat interaction represents a viable target for functional cure therapy. Numerous studies have
determined the structures of HIV TAR in complex with BIV-Tat … strong peptide–RNA binding …

… peptide along with the solution NMR structure of the BIV TAR–Tat complex is shown in …
of the TAR RNA to generate the initial structure of the BIV TAR–Tat complex for simulations. …

… Elongation Complex (SEC) to the HIV promoter. Therefore, TAR has long been a target of …
not between closely related stem-loop structures such as the BIV TAR (28). We now report …

… recent successes in the identification of compounds that target the hepatitis C virus internal
… New structural details are used to model the TAR–Tat–super-elongation complex (SEC) that …

… The primary goal of this study was to determine whether the … RNA complexes in lysates
generated from HEK293 cells that … the native interaction site via the BIV-TAR/TAT system, we next …

… Bovine Immunodeficiency Virus (BIV) Tat–TAR complex. A focused … confirmed the key residues
driving the peptide-RNA … well-characterized RNA targets, such as HIV-1 TAR, is currently …